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Research indicates GSNO increases systemic nitrite levels and delivers nitric oxide to wound sites, promoting enhanced fibroblast collagen synthesis without interfering with matrix metalloproteinase activity required for balanced extracellular matrix turnover

A high cellular antioxidant GSH concentration can protect the cells from oxidative stress

GHK-Cu modulates gene expression across tissue remodeling pathways, including upregulation of collagen types I and III, decorin, and tissue inhibitors of metalloproteinases, while delivering copper to copper-dependent enzymes like lysyl oxidase and superoxide dismutase

Troesch, B., Weber, P., & Mohajeri, M

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